White Papers

  1. EpiSwitch™ Science Chromosome Conformations

    Willem Westra PhD, Ewan Hunter PhD, Alexandre Akoulitchev PhD, Oxford BioDynamics Plc

  2. EpiSwitch™ Technology Overview

    Willem Westra PhD, Ewan Hunter PhD, Alexandre Akoulitchev PhD, Oxford BioDynamics Plc

  3. EpiSwitch™ Biomarker Discovery

    Willem Westra PhD, Ewan Hunter PhD, Alexandre Akoulitchev PhD, Oxford BioDynamics Plc

  4. EpiSwitch™ MIQE- Compliant PCR

    Francis Grand PhD, Willem Westra PhD, Alexandre Akoulitchev PhD, Oxford BioDynamics Plc

  5. EpiSwitch™ Methodology

    Aroul Ramadass PhD, Matthew Salter BSc, Ewan Hunter PhD, Willem Westra PhD, Alexandre Akoulitchev PhD

Recent publications

  1. Generative modeling of multi-mapping reads with mHi-C advances analysis of Hi-C studies.

    Zheng, Y., et. al., Elife January 31, 2019

  2. InTAD: chromosome conformation guided analysis of enhancer target genes.

    Okonechnikov, K., et. al., BMC Bioinformatics January 31, 2019

  3. MACPET: model-based analysis for ChIA-PET.

    Vardaxis, I, et. al., Biostatistics January 30, 2019

  4. Non-coding RNAs and chromatin domains.

    Yamamoto, T., et. al., Curr. Opin. Cell Biol. January 22, 2019

  5. Spatial Principles of Chromatin Architecture Associated With Organ-Specific Gene Regulation

    Chapski, DK., et. al., Front. Cardiovasc. Med. January 15, 2019

  6. Epigenetic chromatin conformation changes in peripheral blood can detect thyroid cancer.

    Surgery (2018) Oct 27. pii: S0039-6060(18)30622-6

  7. Genomic architecture differences at the HTT locus underlie symptomatic and pre-symptomatic cases of Huntington’s disease.

    F1000Research (2018), 7:1757

  8. Initial Identification of a Blood-Based Chromosome Conformation Signature for Aiding in the Diagnosis of Amyotrophic Lateral Sclerosis.

    EBioMedicine (2018) Volume 33, Pages 169–184

  9. The Chromosomal Conformation Signature: A New Kid on the Block in ALS Biomarker Research?

    EBioMedicine (2018) Volume 33, Pages 6–7

  10. Chromosome conformation signatures as a clinical tool for diagnosis, prognosis and disease understanding in ALS

    ENCALS (2018) 20-22 June, Oxford, UK.

  11. White blood cells from Prostate cancer patients carry distinct Chromosome Conformations.

    J of Urology; 199(4S): e452, 2018

  12. Chromosome conformation signatures response to methotrexate in early rheumatoid arthritis.

    J Transl Med (2018) 16:18

  13. A chromosomal conformation signature for a priori prediction of ALS progression subtypes.

    28th International Symposium on ALS/MND; 2017 Dec 8 - 10; Boston, USA